Testes and Ovaries

Biology

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Testis- Origin, Location and Structure

Testis are the male gonads which are the most important organs of the male reproductive system.
Origin
  • Develops from three different layers; The mesothelium (coelomic epithelium), the mesenchyme (intermediate mesoderm) and the primordial germ cells.
Location
  • These are present in a skin pouch called the scrotum located between the upper thighs
Structure
  • They are oval-shaped organs
  • They are made of approximately 900 seminiferous tubules and connective tissue called the stromal or interstitial tissue made of Leydig cells (present adjacent to the seminiferous tubules)
  • The seminiferous tubules consists of seratoli cells along with spermatocytes, spermataozoa and the spermatids.
  • The Leydig cells secrete the androgens (male sex hormones) and the seratoli cells are important for the formation of testis and the spermatogenesis.

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Hormones of the Testis

The testis produces various male hormones collectively called as the androgens.

  1. The androgens include; testosterone, dihydrotestosterone and androstenedione.
  2. Testosterone is considered to be the primary hormone as it is produced abundantly when compared to others.
  3. However, dihydrotestosterone is the more active form. The testosterone is ultimately converted to the active form in the target tissues.
  4. Androgens regulate the development, maturation and function of the male sex organs (e.g. epididymis, seminal vesicles etc.,)
  5. They play an important role in spermatogenesis and male sexual behaviour
  6. They also promote protein and carbohydrate synthesis.

definition

Ovaries- Origin, location and structure

The ovaries are the female gonads that are essential organs of the female reproductive system
Origin
  • Develops from three different layers; The mesothelium (coelomic epithelium), the mesenchyme (intermediate mesoderm) and the primordial germ cells.
Location
  • The ovaries lie in a shallow depression called the ovarian fossae, one on each side of the uterus.
Structure
  • They have an ovoid shape.
  • The ovary has 3 layers; the surface layer, the cortex and the medulla.
  • The surface layer is also called the germinal epithelium (made of simple cuboidal epithelium)
  • The cortex is made of follicles (surrounded by follicular cells) and connective tissue called the stroma. 
  • Estrogen is made by the follicles and hormone-producing tissue in the stroma. 
  • Medulla consists of supporting stroma and contains rich neurovascular network.

definition

Hormones of the Ovary

The ovaries secrete two types of female sex hormones called the estrogens and the progestins. 
Estrogens
  1. In non-pregnant females, they are predominantly secreted by the ovaries. However, during pregnancy, the placenta secretes a lot of estrogens.
  2. The three types of estrogens are; -estradiol, estrone and estriol.
  3. The most active and the principal estrogen produced by the ovaries is the  -estradiol. 
  4. They play an important role in the growth and development of ovarian follicles and breast
  5. They are responsible for the development of secondary sexual characteristics (e.g. high pitch voice)
    They inhibit osteoclastic activity and stimulate bone growth. Osteoporosis in menopausal women is because of reduced estrogen levels.
  6. They also influence the texture of the skin and female sexual behaviour
Progestins (Progesterone)
  1. The progestins are secreted by the corpus luteum, a structure that is formed from the ruptured follicle (after ovulation/ later half of the ovarian cycle).
  2. Most important progestin is the progesterone. Small amounts of 17--hydroxyprogesterone is also secreted along with progesterone.
  3. Placenta also secretes large amounts of progesterone during pregnancy.
  4. The progestins mainly have 2 functions; prepare the uterus for pregnancy and prepare breasts for lactation.
  5. Progesterone acts on mammary glands and stimulates the formation of milk storing sacs called alveoli and milk secretion.

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Testosterone

Testosterone is the male sex hormone secreted by the testes. 
  • It regulates the development of sperms and the secondary sexual characteristics leading to puberty.

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Progesterone

Ovaries produce two hormones, namely, estrogen and progesterone.
  • Progesterone controls the uterine changes during menstrual cycle, and helps in the maintenance of pregnancy.

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Oestrogen

  • They are secreted by the cells of Graafian follicles.
  • It stimulates development of female secondary sex characteristics during puberty and maintain them through the reproductive years of adult life.

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