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Question

Antigen binding site in an antibody is found between
  1. Two light chains
  2. Two heavy chains
  3. Variable regions of heavy and constant regions of the light chains
  4. Variable regions of light and heavy chains

A
Two light chains
B
Two heavy chains
C
Variable regions of light and heavy chains
D
Variable regions of heavy and constant regions of the light chains
Solution
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The antigen-binding site is a region of an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain. It is known as a Fab region also known as Fragment antigen-binding region. Paratope is the antigen-binding site of an antibody.
Therefore, the correct answer is option D.

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