According to Darwin's concept of natural selection, as a struggle for existence, only those organisms could survive which have favourable variation to adapt with the environmental conditions. In other words, struggle for existence results in survival of the fittest which means that natural selection tends to favour those organisms which are most fit to survive with the reproductive age in a particular environment and to produce offspring.
Those organisms that fail to adapt to changes in the environment are likely to become extinct as they won't be able to survive in the changing environment.
So, the correct answer is 'Eventually become extinct'.