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Question

A strand of DNA has the following sequence: 5'-ACTGCCTATGCT-3'.
What is the complementary strand that will be formed when the molecule undergoes replication during the M phase of the cell cycle?
  1. 3' -TGACGGATACGA- 5'
  2. 3'-ACTGCCTATGCT- 5'
  3. 5'-ACTGCCTATGCT-3'
  4. 5'-TGACGGATACGA- 3'
  5. 3'-UGACGGAUACGA-5'

A
3'-UGACGGAUACGA-5'
B
5'-ACTGCCTATGCT-3'
C
3'-ACTGCCTATGCT- 5'
D
5'-TGACGGATACGA- 3'
E
3' -TGACGGATACGA- 5'
Solution
Verified by Toppr

In DNA, Adenine (A) pairs with Thymine (T) and Guanine (G) pairs with Cytosine (C).
Hence, on replication of DNA in M phase, complementary nucleotides for each base pair will be added as follows:
A - T
T - A
G - C
C - G
Since replication occurs in 5'-3' direction, so the complementary strand will be formed in 3'-5' direction.
Hence the sequence of complementary strand formed upon replication will be: 3'-TGACGGATACGA-5'
So, the correct answer is 3'-TGACGGATACGA-5'.

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Similar Questions
Q1
A strand of DNA has the following sequence: 5'-ACTGCCTATGCT-3'.
What is the complementary strand that will be formed when the molecule undergoes replication during the M phase of the cell cycle?
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Q2
What will be the complementary strand sequence of DNA produced during DNA replication of the following given sequence of DNA?
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Q3

Given below is a sample of the portion of a DNA strand with the complementary base sequence on the opposite strand. What does this sequence represent?
5'-GAATTC-3'
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In a double stranded DNA, the sequence of nucleotides in one strand is 3' ATTCGCTAT 5'. What will be the complementary sequence on the other strand?
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Q5
Choose the correct sequence of the complimentary DNA strand produced as a result of replication of the given DNA strand.
3ATGCTGAACT5
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