Slightly less than half of the cholesterol in the body derives from biosynthesis de novo. Biosynthesis in the liver accounts for approximately 10% and in the intestines approximately 15%, of the amount produced each day. The cholesterol biosynthesis pathway involves enzymes that are in the cytoplasm, microsomes (ER), and peroxisomes. Synthesis of cholesterol, like that of most biological lipids, begins from the two-carbon acetate group of acetyl-CoA. Cholesterol synthesis does not occurs in pancreas, spleen and Brunner's gland.
So, the correct answer is 'Liver'
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Q1
Cholesterol is synthesised in
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Cholesterol is necessary for the synthesis of
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Which organelle helps in the synthesis of lipids, cholesterol, steroids and visual pigments in epithelial cells of the retina?
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Q4
Which is/are not the correct function(s) of endoplasmic reticulum?
I. RER is involved in the protein synthesis, and responsible for post-translational modifications of the polypeptide chain.
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Q5
Match the Column-I with Column-II and select the correct option.
Column-I
a. RER
b. SER
Column-II
(i) Detoxification of many poisons
(ii) Synthesis of steroid hormones
(iii) Biosynthesis of cholesterol
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