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Question

Choose the correct answer from the alternatives given :
Discontinuous synthesis of DNA occurs in one strand, because
  1. DNA molecule being synthesised is very long
  2. DNA dependent DNA polymearse catalyses polymerisation only in one direction (5 3)
  3. It is a more efficient process
  4. DNA ligase has to have a role

A
It is a more efficient process
B
DNA dependent DNA polymearse catalyses polymerisation only in one direction (5 3)
C
DNA ligase has to have a role
D
DNA molecule being synthesised is very long
Solution
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The correct option is B DNA dependent DNA polymearse catalyses polymerisation only in one direction (5 3)
The DNA-dependent DNA polymerases catalyze polymerization only in the one direction, that is 5 3. This creates some additional complications at the replicating fork. Consequently, on one strand (the template with polarity 3 5), the replication is continuous, while on the other (the template with polarity 5 3), it is discontinuous. The discontinuously synthesizing fragments are later joined by the enzyme DNA ligase.
So, the correct answer is 'DNA dependent DNA polymerase catalyses polymerisation only in one direction (5 → 3)'.

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