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Question

Component of Ornithine cycle are
  1. Omithine, citrulline and fumaric acid
  2. Amino acids are not used fumaric acid
  3. Ornithine, citrulline and arginine
  4. Ornithine, citrulline and alanine

A
Ornithine, citrulline and arginine
B
Amino acids are not used fumaric acid
C
Omithine, citrulline and fumaric acid
D
Ornithine, citrulline and alanine
Solution
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The urea cycle also known as Ornithine cycle, is a biochemical reaction resulting in the formation of urea from ammonia. It is seen in the ureotelic organism, to convert the toxic ammonia waste to less toxic urea. This reaction takes place when ammonia combines with carbon dioxide forming carbamoyl phosphate, which enters into the cycle and combines with ornithine to form citrulline, at this stage aspartate changes into fumarate, and citrulline to argininosuccinate, which further changes to arginine. Arginine decomposes to give urea out and ornithine. This complete cycle operates at the expense of 4 ATP.
Hence, the correct answer is option A.

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Similar Questions
Q1
Which of these statements are true regarding urea cycle?
1. Fumarate acts as a connecting link between urea cycle and Krebs cycle.2. Urea cycle solely occurs in mitochondria only.3. Citrulline and arginine reacts to form argininosuccinate.4. Ornithine formed in the last reaction is directly excreted along with urea.5. Arginase promotes cleavage of arginine to urea and ornithine.
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Q2
Ornithine is converted into citrulline by the enzyme
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Q3
Which of the following steps are ATP dependent in urea cycle?
I. Combination of ammonia and CO2
II. Conversion of ornithine to citrulline
III. Reaction of citrulline with aspartate
IV. Formation of urea

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Q4
Which of the following statement/statements are not true according to urea cycle?
I. Two ATP molecules are required for synthesis of carbamoyl phosphate.
II. Products of urea cycle are: 1 molecule of urea, 2 molecules of ADP, 1 molecule each of AMP and fumaric acid.
III. Urea cycle takes place in kidney cells.
IV. Reaction of citrulline and aspartate requires ATP.
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Q5
Which of the following steps are ATP dependent in urea cycle?
I. Combination of ammonia and CO2
II. Conversion of ornithine to citrulline
III. Reaction of citrulline with aspartate
IV. Formation of urea

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