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(D) AUG-CUA-GUV-LGU-GUL (C) AUG-CUA-GUL- UAU-UGU Ans (D) 2. Sickle-cell anaemia is due to the following mutant gene: (A) CTC - CAC (B) CTC - GAG (C) CAC - GUG Ans (A) (D) GAG - GUG 3. In the given transcription unit, identify the regions I and II respectively. 1.

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Q1
How many amino acid would be present in the peptide synthesise
from the following mRNA
AUG UUC AAC ACC UAG UUC AUG CCC GAG GGC CAC
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Q2
Sickle-cell anaemia is due to which of the following mutant gene?
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Q3
Go through the following statements
(i) Failure of cytokinesis after telophase stage of cell division results in aneuploidy
(ii) In sickle cell anaemia, there is a single base substitution at the sixth codon of the beta globin gene from GAG to GCG.
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Q4
Given below is sequence of the processed mRNA ready for translation
5' AUG CUA UAC UAA CUG CCA UGC UAG 3'
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Q5
A portion of a gene was sequenced in two individuals. What type of mutation has occurred in individual two?
Individual I:
mRNA: AUGACUCACCGAGCGCGAAGCUGA
Protein: Met−Thr−His−Arg−Ala−Arg−Ser−Stop

Individual II:
mRNA: AUGACUCACUGAGCGCGAAGCUGA
Protein: Met−Thr−His−Stop

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