Question

Dermatitis, diarrhoea and dementia are seen in deficiency of

A

Thiamine

B

Riboflavin

C

Niacin

D

Foliate

Medium
Solution
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Correct option is C)

 

Thiamine () deficiency leads to beriberi disease,Wernicke syndrome,Korsakoff syndrome in alcoholic.

It is essential for growth and repair of tissues,helps to convert tryptophan to niacin and acts as thiamine pyrophophate in TCA cycle.

Riboflavin() deficiency leads to cheilosis ,it helps in erythrocytes production,acts as flavin mononucleotide in electron transport chain and FAD in Krebs cycle.

Niacin() deficiency results in pellagra ,diarrhoea ,dermatitis ,hartnup disease(hereditary disease which leads to inability in the metabolism of tryptophan). It acts as NAD and NADP in Krebs cycle.

Foliate() deficiency causes megaloblastic anemia as it is a primary raw material in the production and maturation of erythrocytes. It checks on the synthesis,proper functioning of neurological system.






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