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Enzymes as Drug Targets

Question

Drugs can inhibit the catalytic activity of enzymes by binding at
active sites
allosteric sites
both active sites and allosteric sites
core of an enzyme

A

allosteric sites

B

both active sites and allosteric sites

C

core of an enzyme

D

active sites

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Solution

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The correct option is C both active sites and allosteric sites
An enzyme inhibitor is a molecule, which binds to enzymes and decreases their activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Drugs can attack both the active as well as the allosteric sites of an enzyme by binding to these sites and decreasing the catalytic activity of the enzymes.

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