The quantifier 'any' is used in negative sentences and interrogatives. The given sentence is an interrogative hence we use 'any' before the noun 'questions'. Option C is hence correct. 'Either' is used when there is a choice to be made between two things or people. Since there isn't any choice mentioned in the given interrogative, there is only one noun, 'questions', hence option A is incorrect. Similarly, 'neither' is the negative form of 'either' and is used when there are two choices in the sentence. Hence option B is incorrect. 'Little' is used to indicate an insufficient quantity of an uncountable noun, the noun 'questions' is countable hence option D is incorrect.
