Question
Assertion

Gastrin is a hormone that is released from the gastrointestinal tract and helps in digestion.

Reason

It promotes secretion of HCl and trypsinogen.

A

Both Assertion and Reason are correct and Reason is the correct explanation for Assertion

B

Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion

C

Assertion is correct but Reason is incorrect

D

Both Assertion and Reason are incorrect

Medium
AIIMS
Solution
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Correct option is C)

  • Gastrin is a peptide hormone that stimulates the secretion of gastric acid (HCl) by the parietal cells of the stomach and helps in gastric motility or digestion.
  •   It is released by G cells in the pyloric antrum of the stomach, duodenum, and pancreas. 
  • Hence, Gastrin is a hormone that is released from the gastrointestinal tract and helps in digestion.
  • The presence of gastrin stimulates parietal cells of the stomach to secrete hydrochloric acid (HCl) or gastric acid.
  •  Trypsin is produced as the inactive trypsinogen in the pancreas. When the pancreas is stimulated by cholecystokinin, it is then secreted into the first part of the small intestine. 
  • Hence, it promotes the secretion of HCl but not of trypsinogen.
  • So, the correct answer is 'Assertion is correct but Reason is incorrect'.

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