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Question

If both the parents have AB blood groups, which of the following blood groups their offspring cannot have?
  1. A
  2. B
  3. AB
  4. O

A
B
B
AB
C
O
D
A
Solution
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The IA allele gives type A, IB gives type B, and IO gives type O. As both IA and IB are dominant over IO, only IO/IO people have type O blood. Individuals with IA/IA or IA/IO have type A blood, and individuals with IB/IB or IB/IO have type B. IA/IB people have both phenotypes, because A and B express a special dominance relationship: codominance, which means that type A and B parents can have an AB child. If both the parents are AB then their genotypes will be IA/IB and this combination cannot give rise to O blood group. Therefore, the correct answer is option D.

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