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Question

In a diploid cell, at which stage of cell cycle, the amount of DNA is doubled
  1. G1 and G2 phase
  2. G0 phase
  3. S, G2 and M-phase
  4. S-phase

A
G1 and G2 phase
B
G0 phase
C
S-phase
D
S, G2 and M-phase
Solution
Verified by Toppr

S phase is the phase of the cell cycle in which DNA is replicated, occurring between G₁ phase and G₂ phase. Following replication, each chromosome now consists of two sister chromatids (see figure below). Thus, the amount of DNA in the cell has effectively doubled, even though the ploidy, or chromosome count, of the cell remains at 2n.

So, the correct answer is 'S-phase'.

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