Question

In higher vertebrates, the immune system can distinguish self-cells and non-self. If the property is lost due to genetic abnormality and it attacks self-cells, then it leads to ?

• A. Allergic response.
• B. Graft rejection.
• C. Auto-immune disease.
• D. Active immunity.

Answer 1

Answer: (C)

Our body's immune system protects us from disease and infection. But if we have an autoimmune disease, our immune system attacks healthy cells in our body by mistake. Autoimmunity is the presence of self-reactive immune response (e.g., auto-antibodies, self-reactive T-cells), with or without damage or pathology resulting from it.