Question

Assertion :In Hoffmann bromide reaction, the amine formed has one carbon atom less than the parent $1^o$ amide. Because Reason: $N-$methyl acetamide undergoes Hoffmann bromamide reaction.

• A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
• B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
• C. Assertion is correct but Reason is incorrect
• D. Assertion is incorrect but Reason is correct

Answer 1

Answer: (C)

The Hofmann rearrangement is the organic reaction of a primary amide to a primary amine with one fewer carbon atoms.The reaction of bromine with sodium hydroxide forms sodium hypobromite in situ, which transforms the primary amide into an intermediate isocyanate via a formation of a nitrene. The intermediate isocyanate is hydrolyzed to a primary amine, giving off carbon dioxide.