| DNA (De-oxyribonucleic acid ) | RNA (Riboucleic acid) |
| DNA usually exists in the double stranded form | RNA predominantly exists in the single-stranded form |
| The monomeric unit: nucleotide of DNA has Deoxy ribose sugar | It is ribose sugar in RNA |
| In
DNA- Purines; Adenine and Guanine (A and G), Pyrimidines; Thymidine and Cytosine (T and C) | In RNA - Purines; Adenine and Guanine (A and G), Pyrimidines; Uracil and Cytosine (U and C) |