Question

Match the following.

List-I	List-II
A. Conjugate vaccine	I. Human papilloma virus
B. Toxoid vaccine	II. Haemophilus influenzae
C. Attenuated whole agent vaccine	III. Bubonic plague
D. Inactivated whole agent vaccine	IV. Yellow fever
	V. Diphtheria

• A. A- II, B- V, C- IV, D- III
• B. A- I, B- II, C- III, D- V
• C. A- II, B- III, C- I, D- IV
• D. A- I, B- IV, C- V, D- II

Answer 1

Answer: (A)

The first glycoconjugate vaccine for use in humans is a Haemophilus influenzae type b (Hib) conjugate. Toxoid vaccine is a vaccine made from a toxin (poison) that has been made harmless but that elicits an immune response against the toxin. They are based on the toxin produced by certain bacteria (e.g., tetanus or diphtheria). Some vaccines contain live, attenuated virus microorganisms. These are live micro-organisms that have been cultivated under conditions that disable their virulent properties, or which use closely-related but less dangerous organisms to produce a broad immune response. They typically provoke more durable immunological responses and are the preferred type for healthy adults. For example, yellow fever, measles, rubella, and mumps. Inactivated whole agent vaccine contain killed microorganisms – these are previously virulent micro-organisms which have been killed with chemicals or heat. For example, vaccines against flu, cholera, bubonic plague, polio and hepatitis A.

Therefore, the correct answer is option A.