Question

Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilization.

• A. Secretin
• B. Gastrin
• C. Insulin
• D. Glucagon

Answer 1

Answer: (C)

Secretin is secreted by endocrine cells of the duodenal wall in response to the presence of hydrochloric acid in chyme and induces the release of pancreatic juice from the pancreas. Insulin serves to lower the blood glucose level by stimulating the uptake of glucose by cells, specifically muscle cells, liver cells and adipose tissues cells. Liver and muscle cells store glucose as glycogen. Glucose serves as energy source for muscle contraction and in adipose tissues, it supplies glycerol for the formation of fat. Glucagon hormone from pancreas stimulates the liver to break down glycogen into glucose and breakdown of fat into glycerol and fatty acids in adipose tissues to serve as a substrate for glucose formation in liver cells. The enteroendocrine cells secrete gastrin which in turn promotes stomach churning and induces more release of gastric juices.

Therefore, the correct answer is option C.