Periodic appearance of malaria symptoms occurs due to periodic
Entry of merozoites into erythrocytes
Attack of liver cells by merozoites
Formation of signet ring
Release of progeny in blood
A
Release of progeny in blood
B
Attack of liver cells by merozoites
C
Entry of merozoites into erythrocytes
D
Formation of signet ring
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Solution
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Paroxysm is the actual attack of malaria which initially begins after a few earliest erythrocyte cycles, but it is, then repeated after every cycle. Obviously paroxysm result due to sufficient accumulation of haemozoin and other toxins in blood.
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