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Question

Semiconservative replication of DNA was first demonstrated in

A
Escherichia coli
B
Salmonella tyhimurium
C
Streptococcus pneumoniae
D
Drosophila melanogaster
Solution
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Correct option is A. Escherichia coli
answer:
Correct Option: A
Explanation:
  • The following are some of the most important experimental proofs that DNA replication is semi-conservative:
1. The experiment of Meselson and Stahl
2. The experiment of Taylor
  • Mathew Messelson and Franklin Stahl (1957-58) established definitively that in intact living E. coli cells, DNA is duplicated in a semi-conservative manner, as Watson and Crick hypothesized.
  • In Vicia faba root tip cells, J.H. Taylor et al. (1958) proved the semi-conservative method of replication in DNA and chromosomes.
Hence, semiconservative replication of DNA was first demonstrated in $${\textit{Escherichia coli.}}$$

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