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Question

Term ‘hybridoma’ implies:


  1. Gametic fusion

  2. Hybrid vigour

  3. Somatic fusion

  4. DNA–RNA hybrid

A

Somatic fusion

B

DNA–RNA hybrid

C

Gametic fusion

D

Hybrid vigour

Solution

The correct option is C

Somatic fusion


Hybridomas are produced by injecting a specific antigen into a mouse, collecting an antibody-producing cell from the mouse's spleen, and fusing it with a tumour cell called a myeloma cell. Since the fusion of protoplasts takes place, it is a type of somatic fusion.

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