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Question

The 3'-5' phosphodiester linkages inside a polynucleotide chain serve to join
  1. One nitrogenous base with pentose sugar
  2. One DNA strand with the other DNA strand
  3. One nucleoside with another nucleoside
  4. One nucleotide with another nucleotide

A
One nucleotide with another nucleotide
B
One DNA strand with the other DNA strand
C
One nitrogenous base with pentose sugar
D
One nucleoside with another nucleoside
Solution
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The correct option is D One nucleotide with another nucleotide
  • A strand of DNA or RNA consists of nucleotides linked together by phosphodiester bonds.
  • A phosphodiester bond exists between the phosphate of one nucleotide and the sugar 3' carbon of the next nucleotide.
  • This forms a backbone of alternating sugar and phosphate molecules known as the sugar-phosphate backbone.
  • The two strands of DNA are also antiparallel (run in opposite directions) to one another. A strand of DNA can have direction 5'-3' or 3'- 5'.
  • One strand of the DNA molecule is 5'-3' and the other strand is 3'-5'. A DNA strand is assigned direction based on what is found at the end of the strands.
  • The end of the strand with a free phosphate is the 5' end because phosphate attaches to the 5' carbon of the sugar.
  • The end with a free OH group is the 3' end because the OH group is attached to the 3' carbon of the sugar.
So, the correct answer is option D.

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Similar Questions
Q1
Match the following and find the correct option.
I II
(a) Hydrogen bond(i) Adenine - deoxyric base
(b) N-glycosidic linkage(ii) Glucose - Fructose
(c) Phosphodiester bond(iii) Leucine - Glycine
(d) Peptide bond(iv) Nucleotide - Nucleotide in polynucleotide chain
(v) Guanine - Cytosin on opposite strands of DNA

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Q2
The 3'- 5' phosphodiester linkages inside a polynucleotide chain serve to join

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Q3
Pentose sugar + nitrogen base = nucleoside
nucleoside + phosphate = nucleotide
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Q5
Assertion :The sugar phosphate backbone of two chains in DNA double helix show anti-parallel polarity. Reason: The phosphodiester bonds in one strand go from a 3 carbon of one nucleotide to a 5 carbon of adjacent nucleotide, whereas those in complementary strand go vice versa.
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