The given word 'rejuvenation' means 'the action of restoring to a former state, feeling better or more vital'. For example, 'the massage made me feel rejuvenated.'
An antonym is a word that is opposite in meaning to another word.
From the options, 'destruction' means 'the action of causing so much damage that it cannot be repaired.' For example, 'the recent mob caused a great deal of destruction in the city.' It is the opposite of the given word. The former refers to renewal whereas the latter refers to damage. Hence it is the antonym and option C is correct.
'Reinvigoration' means 'impart strength or vitality to', it is synonymous to the given word.
'Perfection' means 'a state or quality of being flawless'; it has no connection with the given word.
'Reconciliation' means 'restoring a relationship or a friendship'. Again, this has no connection with the given word. (The former refers to social restoration whereas the latter refers to restoring health or the mind.)
Hence these words are not antonyms and otions A, B and D are incorrect.