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Question

The $$pK_{a}$$ of acetylsalicylic acid (aspirin) is $$3.5$$. The $$pH$$ of gastric juice in human stomach is about $$2$$ to $$3$$ and the $$pH$$ in the small intestine is about $$8$$. Aspirin will be

A
unionized in the small intestine as well as in the stomach.
B
ionized in the stomach and almost unionized in the small intestine.
C
ionized in the small intestine and almost unionized in the stomach.
D
completely ionized in the small intestine as well as in the stomach.
Solution
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Correct option is D. ionized in the small intestine and almost unionized in the stomach.

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