Question

The reaction of primary amine with chloroform and ethanolic solution of $KOH$ is called :

• A. Hofmann reaction
• B. Reimer-Tiemann reaction
• C. Kolbe reaction
• D. Carbylamine reaction

Answer 1

Answer: (D)

This reaction is a chemical test for detection of primary amines, in which the amine is heated with alcoholic potassium hydroxide and chloroform. If a primary amine is present, the isocyanide is formed. The reaction is known as carbylamine reaction.

$RN{H}_2+CHC{l}_3+3KOH\to R{N}^{+}\equiv C^{-}+3KCl+3H_{2}O$