The correct option is B Concentration of urea goes high in the blood because the tubules are not able to remove it from the blood
Urea is very soluble and a small molecule, so it is relatively easily passed out by the kidneys as a solution in water. Uraemia is an excretory disorder in which there is increased level of urea in the blood. It is caused due to the renal failure. In uremia, the tubular absorption of urea in collecting duct is inhibited. Progressive weakness and easy fatigue, loss of appetite due to nausea and vomiting, muscle atrophy, are some common symptoms of ureamia.