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Question

What is intrinstic factor-X-activator complex?
  1. XII+FSF+Glycolipid+Ca2+
  2. IX+AHF+Glycolipid+Ca2+
  3. XII+FSF+Phospholipid+Ca2+
  4. IX+AHG+Phospholipid+Ca2+

A
XII+FSF+Glycolipid+Ca2+
B
IX+AHF+Glycolipid+Ca2+
C
XII+FSF+Phospholipid+Ca2+
D
IX+AHG+Phospholipid+Ca2+
Solution
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The intrinstic factor-X-activator complex is formed during blood coagulation. The zymogen factor X is converted to its active form factor Xa by intrinstic factor-X-activator complex. This complex consists of a protease factor IX which along with its cofactor, factor VIII assembles on a phospholipid surface. Factor VIII is also known as antihemophillic globulin or AHG. Calcium ions are also required during blood coagulation for the formation of this complex.
Hence, intrinstic factor-X-activator complex is IX + AHG + Phospholipid + Calcium ions.
So, the correct answer is D.

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