It is the responsibility of the urinary system to create urine and excrete or remove waste material from the body. Kidneys, ureters, and urethra are important organs of the urinary system. In the integumentary system, waste is also removed from the body through sweat glands and through the digestive and excretory systems. The primary route through the kidneys in which the body eliminates drugs. The kidney's primary role is the excretion into the urine of body waste and damaging chemicals. The nephron is the kidney's functional unit responsible for excretion. There are about one million nephrons in each kidney. In the renal excretion phase, the nephron has three main areas: the glomerulus, the proximal tubule, and the distal tubule. Three processes are involved in urinary excretion: Filtration, Secretion, Reabsorption.