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Question

What is the probability of X-linked genes being passed from father to son?
  1. 0%
  2. 50%
  3. 100%
  4. 25%

A
0%
B
25%
C
50%
D
100%
Solution
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Human females have forty-six chromosomes arranged in twenty-two homologous and homomorphic autosomes and two copies of X chromosomes as sex chromosomes (44+XX). Males have twenty-two homomorphic pairs and one heteromorphic pair, the XY pair (44+XY). The X chromosome in human follows criss-cross inheritance wherein father transmits its only X chromosome to the daughters while mother passes both X chromosomes to her sons. Thus, the X-linked genes, present on X-chromosomes, cannot be transmitted from father to son. Thus, the correct answer is option A.

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