The binding energy is the energy released when a nucleus is assembled from its constituent nucleons. It is thus a measure of the amount of energy held within the bonds of the atom and corresponds to the energy required to be put in again to pull the nucleons apart. Hence, the energy equivalent of the mass-defect is called the binding-energy of the nucleus.
The larger the nucleus, the greater is the internal repulsive forces due to the greater number of protons and less energy must be applied to remove a nucleon from the nucleus, hence the binding energy is lower. The greater the binding energy, the more stable the atom is.
This variation in the binding energy per nucleon (BEA) is easily seen when the average BEA is plotted versus atomic mass number (A), as shown in the figure, as the atomic mass number increases i.e. the number of particles in a nucleus increases, the total binding energy also increases first and then decreases for A > 56.