Question

Which hormones stimulate the production of pancreatic juice and bicarbonate ions?

A

Cholecystokinin and secretin

B

Insulin and glucagon

C

Angiotensin and epinephrine

D

Gastrin and insulin

Hard
NEET
Solution
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Correct option is A)

The enteroendocrine cells secrete gastrin which in turn promotes stomach-churning and induces more release of gastric juices. Secretin and cholecystokinin are secreted by endocrine cells of the duodenal wall in response to the presence of hydrochloric acid in chyme and that of fatty food respectively. Secretin induces the release of pancreatic juice from the pancreas while cholecystokinin induces contraction of the gall bladder to release stored bile. Insulin and glucagon regulate blood sugar level. Angiotensin is a decapeptide, attached to the liver plasma protein angiotensinogen and is released by renin. Epinephrine is one of the stress hormones. 
So, the correct answer is 'Cholecystokinin and secretin'.

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