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Question

Which of the following reaction needs catalyses by decarboxylase enzyme?

  1. Conversion of citric acid to cis-aconitic acid
  2. Fumaric acid to malic acid
  3. Oxalosuccinic acid to α-ketoglutaric acid
  4. Malic acid to oxaloacetic acid

A
Conversion of citric acid to cis-aconitic acid
B
Oxalosuccinic acid to α-ketoglutaric acid
C
Fumaric acid to malic acid
D
Malic acid to oxaloacetic acid
Solution
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Oxalosuccinate is decarboxylated to form α-ketoglutarate through the enzyme decarboxylase. It is one of the steps involved in Krebs cycle. It releases one molecule of CO2.
OxalosuccinateDecarboxylaseMg2+α-ketoglutarate+CO2

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