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Question

Which of the following is an example of sex linked character in man?
  1. Colour blindness
  2. Haemophilia
  3. ABO-blood groups
  4. Haemophilia and colour blindness

A
Haemophilia and colour blindness
B
Haemophilia
C
Colour blindness
D
ABO-blood groups
Solution
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The correct option is D Haemophilia and colour blindness
One example of an X-linked trait is red-green colorblindness. Let (Xc) represent the recessive allele that causes colorblindness and (X+) represent the normal dominant allele. Females that are X+X+ or X+Xc have normal color vision, while XcXc females are colorblind. Males that are X+Y have normal color vision, while XcY males are colorblind. Hemophilia is inherited in an X-linked recessive pattern. A condition is considered X-linked when gene mutation that causes it is located on the X chromosome, one of the two sex chromosomes. In males (who have only one X chromosome), one altered copy of the gene in each cell is enough to cause the condition. Since females have two X chromosomes, a mutation must be present in both copies of the gene to cause hemophilia. Males are affected by X-linked recessive disorders much more frequently than females. A major characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons. Thus, option D is correct and other options are wrong.

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