Which one of the following pairs correctly matches a hormone with a disease resulting from its deficiency : -
Relaxin Gigantism
Prolactin Cretinsim
Parathyroid hormone Tetany
Insulin Diabetes insipidus
A
Relaxin Gigantism
B
Parathyroid hormone Tetany
C
Prolactin Cretinsim
D
Insulin Diabetes insipidus
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Solution
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Gigantism is a rare condition of accelerated growth and increased height as a result of too much growth hormone secretion during childhood or adolescence. It is almost always the result of a growth hormone-secreting pituitary tumour.
Congenital hypothyroidism (under activity of the thyroid gland at birth), which results in growth retardation, developmental delay, and other abnormal features. Cretinism can be due to a deficiency of iodine in the mother's diet during pregnancy.
Hypoparathyroidism is decreased function of the parathyroid glands with underproduction of parathyroid hormone. This can lead to low levels of calcium in the blood, often causing cramping and twitching of muscles or tetany (involuntary muscle contraction) and several other symptoms.
Diabetes mellitus occurs due to insulin resistance or insulin deficiency and subsequent high blood glucose levels. Diabetes Insipidus, on the other hand, develops as a result of the stilted production of a hormone in the brain, which is released to stop the kidneys producing so much urine in order to retain water.
So, the correct answer is 'Parathyroid hormone Tetany'.
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