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Question

Write the reactions involved in the following.
Gabriel phthalimide synthesis.

Solution
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Gabriel phthalimide synthesis:
Phthalimide reacts with ethanolic KOH to give potassium salt of phthalimide. It is then heated with alkyl halide to give N-alkyl phthalimide. On alkaline hydrolysis, a primary amine is obtained.
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Similar Questions
Q1
Write the reactions involved in the following.
Gabriel phthalimide synthesis.
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Q2
Write about Gabriel phthalimide synthesis?
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Q3
Which of the following steps is not present in Gabriel phthalimide synthesis?
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Q4
(a) Write the reactions involved in the following:

(i) Hoffmann bromamide degradation reaction

(ii) Diazotisation

(iii) Gabriel phthalimide synthesis

(b) Give reasons :

(i) (CH3)2NH is more basic than (CH3)3N in an aqueous solution.

(ii) Aromatic diazonium salts are more stable than aliphatic diazonium salts.
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Q5

Write short notes on the following:

(i) Carbylamine reaction

(ii) Diazotization

(iii) Hofmann's bromamide reaction

(iv) Coupling reaction

(v) Ammonolysis

(vi) Acetylation

(vii) Gabriel phthalimide synthesis.

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