Semiconservative replication of DNA

A complex structure that has the ability to control us

It has a double helical structure made of nucleotides is our genetic material

It is known as DNA or Deoxyribonucleic acid.

The complete detailed structure of DNA was given by two scientists Watson and Crick in 1953.

As to transfer from one generation to another it needs to replicate to maintain the originality of information.

Initially, it was believed that DNA completely replicate itself

That means the complete DNA helix forms another helix.

This belief continues for a long time. But the truth can’t be hidden for a long time.

So lets reveal the truth behind this mysterious replication

During the S phase of mitosis the DNA replicates itself.

For the replication of DNA Watson and Crick proposed a mechanism.

Which is entirely based on the double helical structure given by them.

Lets see the mechanism

During replication, the hydrogen bond present between the two nucleotides break.

This makes the two strands of DNA uncoil and break.

We all know that the base pairs of DNA strands are specific.

Due to which they attract their complementary nucleotides present in the cytoplasm.

As the complementary nucleotides come nearer they again form the hydrogen bond.

The sugar radicals are joined by the phosphate group.

This results in the formation of the new polynucleotide chain.

This explanation was different and interesting.

It suggested that each strand of parent DNA acts as a template.

On which only one new daughter strand form.

And this is the reason the replication of DNA is known as Semi conservative as it has one old and one new strand.


Replication of the DNA mechanism was proposed by Watson and Crick.

They said that after the hydrogen bond break the complementary nucleotide from cytoplasm makes the bond with DNA nucleotides.

The sugar radicals again attached by the phosphate group.

And new DNA is formed.

This is known as Semiconservative replication as one older strand and one newly synthesized strands are present.

The End