Azelaic Acid Formula

What is Azelaic Acid?

This article deals with azelaic acid formula. Azelaic acid refers to an organic compound that exists as a white powder. Furthermore, one can find it in wheat, barley, and rye. It is an important ingredient to various industrial products including plasticizers and polymers. Moreover, azelaic acid is a dicarboxylic acid that occurs naturally. Azelaic acid has comedolytic, keratolytic, and antibacterial characteristics.

Azelaic acid is bactericidal against staphylococcus epidermis and proprionibacterium acnes. This is due to the inhibitory effect of azelaic acid on the synthesis of microbial cellular proteins. Furthermore, azelaic acid shows its keratolytic and comedolytic characteristics by diminishing the stratum corneum’s thickness. Moreover, it also decreases the keratohyalin granules by diminishing the distribution as well as the amount of filaggrin in the epidermal layers.

Derivation of Azelaic Acid Formula

Azelaic acid is known as a nonanenoid acid. This acid can be obtained both naturally and at the industrial level. Naturally, one can produce it by a yeast whose name is Malassezia furfur. This yeast mostly exists on the skin. At an industry level, one can obtain azelaic acid by the ozonolysis of oleic acid.

The property value of the hydrogen bond acceptor is 2. Moreover, the property value of the hydrogen bond donor is 4. Furthermore, the rotatable bond count is 8. Most noteworthy, the molecular formula of azelaic acid is \(C_{9}H_{16}O_{4}\). Also, the simplified molecular input line entry system of azelaic acid is OC(=O)CCCCCCCC(O)=O.

Properties of Azelaic Acid

The appearance of azelaic is like a yellowish to white crystalline powder. Moreover, the boiling point of this compound happens to be 286.5 °C at 1.00E+02 mm Hg. Moreover, the melting point of azelaic acid is 106.5 °C. Also, the flash point of this compound is at 210 °C (closed cup).

The solubility of azelaic acid happens at 2400 mg/L (at 20 °C). Furthermore, this acid is slightly soluble in benzene, ethyl ether, and DMSO. Moreover, azelaic acid is soluble in ethanol. Furthermore, this compound is soluble in organic solvents, alcohol, and water. Above all, one liter of water can dissolve 1.0 g of azelaic acid at 1.0 °C. The density of azelaic acid happens to be 1.225 g/cu cm at 25 °C. The vapor pressure of this compound is 1.07e-08 mmHg.

Uses of Azelaic Acids

Esters of this acid have considerable applications in lubrication and plasticizers. In lubricant industries, azelaic acid usage takes place as a thickening agent in lithium complex grease. With hexamethylenediamine, azelaic acid results in the formation of Nylon-6,9, which has special uses as a plastic.

Experts make use of azelaic acid to treat mild to moderate acne, both inflammatory acne, and comedonal acne. It belongs to a class of medication whose name is dicarboxylic acids. Furthermore, it works by killing acne bacteria that have a negative impact on skin pores. Moreover, it also decreases keratin production, which happens to be a natural substance that facilitates the growth of acne bacteria.

Experts also make use of azelaic acid as a topical gel treatment for rosacea. This is because of its ability to reduce inflammation. Furthermore, It clears the bumps and swelling that are due to rosacea. Experts also make use of azelaic acid for treatment of skin pigmentation including postinflammatory hyperpigmentation and melasma, especially dark skin type. Moreover, experts recommend azelaic acid as an alternative to hydroquinone. As a tyrosinase inhibitor, azelaic acid has the ability to diminish the synthesis of melanin.

Solved Question For You

Question: What is the formula of Azelaic acid?

Answer: The molecular formula of azelaic acid is \(C_{9}H_{16}O_{4}\). On the other hand, the simplified molecular input line entry system for azelaic acid happens to be OC(=O)CCCCCCCC(O)=O.